TFRC and neoplasm: Besides, we also analyze whether CD71 and Claudin18.2 were expressed only in tumor cells or in other cells of the tumor microenvironment by analyzing a single-cell database of clinical gastric cancer patients (GSE167297), and the cell subpopulations obtained based on an unsupervised clustering algorithm were shown in Fig. 1E. The expression of CD71 and Claudin18.2 in different subpopulations of cells was analyzed, and it was found that these two molecules were mainly expressed in epidermal cells with cancerous properties (Fig. 1F).