BCR and chronic myelogenous leukemia, BCR-ABL1 positive: Chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL) are hematological malignancies driven by Breakpoint Cluster Region-Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) fusion oncoprotein, which constitutively activates tyrosine kinase signaling and promotes malignant proliferation and survival (1, 2).