A risk model based on 10 mitophagy genes (e.g., activating molecule in beclin-1-regulated autophagy [AMBRA1], autophagy-related 14 [ATG14], microtubule-associated protein 1 light chain 3 beta [MAP1LC3B]) can effectively stratify patients with CRC into high-risk and low-risk groups. This evidence concerns the gene ATG14 and colorectal carcinoma.