In breast cancer (BC), cancer-associated fibroblasts (CAFs) transport mitochondria through tunneling nanotubes (TNTs), enhancing cancer cell oxidative phosphorylation (OXPHOS) and migration,112 with recent evidence showing that mitochondrial transfer from adipose stem cells can drive multi-drug resistance by increasing OXPHOS and ABC transporter expression.113. This evidence concerns the gene ABCG2 and breast cancer.