Laboratory testing showed leukocytosis (25.7 × 103/μL), anemia (hemoglobin 7.5 g/dL), thrombocytopenia (27 × 103/μL), CRP 335 mg/dL, impaired renal function (eGFR 22 mL/min), hypoalbuminemia (17.7 g/L), elevated ferritin (3,571 ng/mL), soluble interleukin-2 receptor (sIL-2R, 16,700 IU/mL), interleukin-6 (IL-6, 124pg/mL), and vascular endothelial growth factor (VEGFa, 998pg/mL) but no relevant gammaglobulinemia (Table 1). The gene discussed is VEGFA; the disease is anemia (phenotype).