Statistical analysis was carried out using one-way ANOVA followed by the Student-Newman-Keuls (p < 0.05).<h4>Results</h4>Hepatic levels of TLR4 and NF-κB were significantly higher in AP and Alcohol+AP groups compared to Control and Alcohol groups (p < 0.05). This evidence concerns the gene NFKB1 and alkaline phosphatase measurement.