CHEK1 and pancreatic neoplasm: The results of the univariate analysis, as depicted in Fig 2C, suggest that CHEK1 (Hazard Ratio, HR = 1.87578, p = 0.00003), age (HR = 1.02755, p = 0.00958), and grade (HR = 1.45334, p = 0.01028) significantly influence the prognosis of pancreatic cancer.