Viral FADD-like interleukin-1-β-converting enzyme inhibitor protein [FLICE/caspase 8] (vFLIP-ORF 71), a homologous protein of cellular FLIP (cFLIP), is expressed during latent infection and has been shown to be essential for the survival of infected tumor cells due to antiapoptotic functions, autophagy suppression and NF-κB activation (Grossmann et al. 2006; Lee et al. 2009) (Figs.4 and 5B). This evidence concerns the gene NFKB1 and neoplasm.