<h4>Background</h4>The role of the long noncoding RNA ZEB1-AS1 in cardiac hypertrophy (CH) remains unclear.<h4>Objectives</h4>To investigate the function of ZEB1-AS1 in the development and progression of CH as well as elucidate its underlying molecular mechanism.<h4>Methods</h4>RNA expression levels were quantified by quantitative real-time PCR. Here, ZEB1 is linked to cardiac hypertrophy.