Hypermethylation of PELI1 occurred in colon adenocarcinoma (COAD), HNSC, KIRC, LUAD, READ, SKCM, thyroid carcinoma (THCA) and UCEC (Supplementary Figure S1A), while hypomethylation was observed in kidney renal papillary cell carcinoma (KIRP), LIHC, prostate adenocarcinoma (PRAD) (Supplementary Figure S1A). This evidence concerns the gene PELI1 and reading.