SOAT1 and alcohol dependence: The enrichment analysis revealed that the upregulated gene pathways primarily involve “Cytokine-cytokine receptor interaction,” “ECM-receptor interaction,” “JAK-STAT signaling pathway,” “Hematopoietic cell lineage,” and “Viral protein interaction with cytokine and cytokine receptor.” In contrast, the major downregulated pathways include “Alcoholism,” “DNA replication,” “Biosynthesis of cofactors,” “Cell cycle,” “Fanconi anemia pathway,” “Base excision repair,” “Aminoacyl-tRNA biosynthesis,” and “Purine metabolism.”