APOB and heart disorder: From the PASC-only cohort, we found several candidates with known functions in the heart and CNS: apolipoprotein B (APOB), a carrier for clinically significant lipids, such as low-density lipoprotein (LDL), which not only has a strong genetic association with susceptibility to heart disease and stroke (Richardson et al., 2021) but whose rare variants are also associated with early-onset AD (Wingo et al., 2019).