Novel loci, such as mucin 4 (MUC4), mucin 16 (MUC16), Janus kinase 1 (JAK1), interferon regulatory factor 1 (IRF1), interferon alpha 10 (IFNA10), calcium and integrin binding family member 4 (CIB4), nephronectin (NPNT), zinc finger with KRAB and SCAN domains 1 (ZKSCAN1), ATPase phospholipid transporting 11A (ATP11A), and proteasome 26S subunit, non-ATPase 3 (PSMD3), were also associated with variable COVID-19 morbidity. The gene discussed is JAK1; the disease is COVID-19.