In this single-center study conducted at a safety-net hospital, non-liver-related variables including age, sex, BMI, various comorbidities, respiratory support requirement at admission, increases in creatinine, decreases in platelets, and decreases in albumin were associated with severe COVID-19 in our cohort, consistent with previous studies (8, 27, 33, 44–46, 55–59, 61). Here, ALB is linked to COVID-19.