Spearman correlation revealed that MRPs was negatively correlated with ImmuneScore (R = –0.26), StromalScore (R = –0.23), and ESTIMATEScore (R = –0.26), but positively correlated with TumorPurity (R = 0.25), all statistically significant (Figure 5C), reinforcing the notion that higher MRPs scores are linked to an immunologically "cold" tumor phenotype. The gene discussed is MRPS7; the disease is neoplasm.