To investigate the prognostic differences between patients with various clinical and pathological characteristics who received BCS and mastectomy, we subdivided them according to different variables (age, tumor location, clinical T stage, clinical node status, tumor subtype, tumor grade, presence of DCIS in pre-NAT biopsy, Ki-67 index, and pCR) and conducted stratified multivariate Cox proportional risk regression analysis on the effects of the surgical procedure (BCS and mastectomy) on OS (Table 3) and DFS (Table 4). This evidence concerns the gene MKI67 and neoplasm.