IL1A and cancer: Members of the IL-1 family exhibit pleiotropic effects in the organism; they are mediators of inflammation in the body (22, 24, 36, 37, 54), they are involved in the innate and acquired immune response (22), they influence the regulation of angiogenesis and vascular permeability (23, 36), and their action has been described as a pathological mediator of many diseases, especially those with autoimmune, infectious and degenerative backgrounds (36), as well as cancer (23, 36).