Therefore, the aim of the present study was to analyze the concentrations of all 11 members of the IL-1 family (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ, IL-37, IL-1Ra, IL-36Ra, IL-38) in the serum and peritoneal fluid of patients with ovarian cancer and to determine the relationship between the parameters studied and the degree of histological differentiation of ovarian cancer. Here, IL1R1 is linked to ovarian cancer.