While its role in PCa has been underexplored, NR2F1-AS1 has been reported to regulate proliferation, invasion, migration, apoptosis, and metabolic pathways in various cancers, including HCC, gastric, colorectal, pancreatic, esophageal, breast, lung, and thyroid cancers (Huang et al., 2018; Tarchini et al., 2018; Guo et al., 2019; Zhang et al., 2019; Sanchez Calle et al., 2020; Wang et al., 2020; Yang et al., 2020; Zhang C. et al., 2020; Zhang Q. et al., 2020; Li et al., 2021b; Liao et al., 2021; Luo et al., 2021; Lv et al., 2021). Here, NR2F1 is linked to thyroid cancer.