Significant associations (P < 0.05) were observed between the high-risk group and multiple immune cell types, including Myeloid dendritic cells (activated, XCELL), CD4+ central memory T cells (XCELL), naive CD8+ T cells (XCELL), M2 macrophages (QUANTISEQ), non-regulatory CD4+ T cells (QUANTISEQ), uncharacterized cells (QUANTISEC), CD8+ T cells (TIMER), neutrophils (TIMER), cancer-associated fibroblasts (EPIC), endothelial cells (EPIC), macrophages (EPIC), naive B cells (CIBERSORT), and follicular helper T cells (CIBERSORT) (Figure 5B). The gene discussed is CD8A; the disease is cancer.