Recent studies by the Eilers group added further nuance: MYC protein has been observed to multimerize at stalled replication forks (Solvie et al., 2022), and MYCN can recruit the nuclear exosome targeting complex to nascent RNAs leading to S phase progression and tumour cell stress resilience (Papadopoulos et al., 2024). This evidence concerns the gene MYC and neoplasm.