Western blot analysis detected apoptosis-related proteins, the results indicated that the anti-apoptotic protein Bcl-2 was inhibited in silicosis (p = 0.005, 95%CI = 0.20–0.31), while the pro-apoptotic protein was activated (p = 0.016, 95%CI = −0.08 to −0.02). Here, BCL2 is linked to silicosis.