Sensitivity analyses showed that results were still significant after adjusting the model for hypertension status (ρ = 0.082 [0.021, 0.142], p = 0.008), CAIDE-I score (ρ = 0.090 [0.030, 0.150], p = 0.003) and APOE-ε4 carriership (ρ = 0.062 [0.001, 0.122], p = 0.048; Figure 1A; Table 2). The gene discussed is APOE; the disease is Hypertension.