MED13 and intervertebral disk degenerative disorder: Intellectual developmental disorder (IDD), autosomal dominant 61 (MRD61; OMIM 618009), also referred to as MED13-related syndrome, is a rare autosomal dominant disorder [1] caused by heterozygous pathogenic variants in the MED13 gene, which encodes a subunit of the Mediator complex that regulates transcription by RNA polymerase II [2].