The efficacy of immunotherapy and adrenocorticotropic hormone (ACTH) in the treatment of infantile epileptic spasms syndrome could be due, at least in part to the anti-inflammatory and immunosuppressive properties of these compounds (Choi and Koh, 2008; Barker-Haliski et al., 2017). The gene discussed is POMC; the disease is infantile spasms.