Clinical studies have shown that WXKL may suppress sarcoplasmic reticulum Ca2+ release and maintain intracellular Ca2+ balance,[7] regulate mitochondrial function and homeostasis,[8] regulate the CaMK II signal transduction pathway to inhibit arrhythmia and improve cardiac function.[9] Accumulating evidence from various animal and cell studies has shown that WXKL could protect the myocardium and anti-arrhythmia against cardiovascular diseases. The gene discussed is CAMK2G; the disease is cardiac arrhythmia.