Genetic factors[5-7] contribute to the disease by affecting insulin sensitivity and the function of pancreatic β-cell.[8-10] Environmental factors such as unhealthy dietary habits, lack of physical activity, overweight, and obesity significantly increase the risk of developing this disease.[11,12] Additionally, age, ethnicity, and family history are also significant risk factors for T2D.[13,14]. Here, INS is linked to type 2 diabetes mellitus.