Type 2 diabetes (T2D) is a chronic metabolic disorder characterized primarily by hyperglycemia, insulin resistance, and a relative deficiency in insulin secretion.[1-3] According to the World Health Organization (WHO), T2D is the most prevalent form of diabetes globally, posing a significant challenge to public health worldwide.[4] The pathogenesis of T2D is complex, involving an interplay between genetic and environmental factors. Here, INS is linked to type 2 diabetes mellitus.