ALK and inflammatory myofibroblastic tumor: Nonetheless, adjuvant radiotherapy and chemotherapy should be considered as potential treatment options.[43] Some evidence suggests that ALK-negative IMTs may have a greater propensity for metastasis.[1,41,44] Cheryl M. et al reported a correlation between ALK negativity and local recurrence, but not with distant metastasis.[41] However, the prognostic significance of ALK negativity in IMT remains unclear.