TNF and neurodevelopmental disorder: Inflammatory factors such as TNF-α, IL-1β, and IL-6 can exacerbate white matter injury through pathways such as blood–brain barrier disruption, oligodendrocyte apoptosis, and myelin formation disorders, ultimately leading to motor and cognitive dysfunction.[6,20–22] In recent years, the rise of keywords such as “inflammation” and “children” reflects the expansion of CP research towards inflammation-mediated neurodevelopmental disorders and long-term functional prognosis.