We implemented a dual scoring system for risk quantification: IPSET-thrombosis score: 79 years old (2 points) + JAK2 mutation (1 point) + recent STEMI (2 points), totaling 5 points indicating extremely high risk; HAS-BLED score: >75 years old (1 point) + renal insufficiency (1 point), totaling 2 points indicating moderate bleeding risk. This evidence concerns the gene JAK2 and Renal insufficiency.