To investigate potential disease subtypes within AAA, we employed consensus clustering and categorized all AAA patients into two subgroups, A and B. Notably, the expression of senescence-related biomarkers IL6, ETS1, and TDO2 differed significantly between these two subgroups, suggesting that senescence-related gene expression may serve as a key indicator for AAA subtyping. The gene discussed is TDO2; the disease is triple-A syndrome.