CCN6 and breast cancer: Of note, we obtained a distinct gene expression profile, including increased expression of WISP3, a gene that has been previously associated with aggressive inflammatory breast cancer and breast cancer metastasis [42–44], and CCNA1 (Cyclin A1) a canonical cyclin that promotes S and G2 phase progression, previously reported to be overexpressed in up to 82% of AML cells [45–48].