LMX1B and Parkinson disease: Relevantly, homozygous conditional knockout of both Lmx1b and Lmx1a, as well as siRNA knockdown of Lmx1b alone, impacts mitochondrial functions in neurons and may contribute to Parkinson’s disease (Jiménez-Moreno et al., 2023; Doucet-Beaupré et al., 2016; Bergman et al., 2009).