To investigate whether recurrent cytogenetic aberrations correlate with aging‐related DNAm changes, we stratified the AML cohort into ten cytogenetic subgroups based on cytogenetic and molecular criteria in European LeukemiaNet recommendations [36] (e.g., CBFB::MYH11 fusion and MLLT3::KMT2A fusion) (Figure S5A). The gene discussed is CBFB; the disease is acute myeloid leukemia.