We evaluated correlations between AdaptAge subgroups and probability of OS in three distinct populations: the full TCGA AML cohort, CN‐AML subgroups, and CN‐AML subgroups harboring common mutations in seven DNA methylation‐related genes (DNMT1, DNMT3A, DNMT3B, IDH1, IDH2, TET1, and TET2) [28]. The gene discussed is DNMT3B; the disease is acute myeloid leukemia.