They considered in the clinical-radiological model the following parameters as predictor factors of MVI: (1) AST > 40 U/L, (2) AFP > 400 ng/mL, (3) non-smooth tumour margin, (4) extrahepatic growth pattern, (5) ill-defined pseudo-capsule, (6) peritumoural arterial enhancement, and (7) radiographic venous invasion.23 The gene discussed is AFP; the disease is neoplasm.