GDF‐15 correlated with hepatic dysfunction (MELD Spearman's ρ: 0.50; albumin ρ: −0.57), HVPG (ρ: 0.47), systemic inflammation (C‐reactive protein ρ: 0.45; interleukin 6 [IL‐6] ρ: 0.55; procalcitonin ρ: 0.58), liver stiffness (ρ: 0.67) and enhanced liver fibrosis test (ρ: 0.64) (all p < 0.001). Here, IL6 is linked to Hepatic fibrosis.