Further STRING analysis of Pbx1 interactome revealed several associations with histone modifiers and methyltransferases identified in our mass spectrometry results, including Kmt2a and Smarca4, as well as with MNX1’s translocation partner Etv6 in t(7;12) AML and several other homeobox proteins (Supplementary Table S7). Here, SMARCA4 is linked to acute myeloid leukemia.