Findings indicate that BSP promotes EMT-mediated anoikis resistance in NSCLC cells via MMP-14-dependent ERK activation and suppression of microRNA (miR)-150-5p synthesis.135 While miR-150-5p typically promotes tumour progression by enhancing survival and suppressing apoptosis,136 its role can be context-dependent, with both oncogenic and tumour-suppressive effects.137. Here, IBSP is linked to non-small cell lung carcinoma.