The TCF19 gene (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{upgreek}\usepackage{mathrsfs}\setlength{\oddsidemargin}{-69pt}\begin{document}$P=2.57\times 10^{-7}$\end{document}) has been significantly associated with various autoimmune diseases and human cancers (including cervical cancer and autoimmune thyroiditis), but its association with RA remains unclear. The gene discussed is TCF19; the disease is autoimmune disease.