EGFR and coinfection: Taking into consideration the TCE production and oncolytic activity data, we decided to focus our analysis on dual-targeting with the Db-TriTE-encoding virus (Ad5/3-DMFE), co-expression of scDb-cMET and taFv-EGFR (Ad5/3-DMTtE), and co-infection (Ad5/3-tE + Ad5/3-DM).