TNF and Thrombocytopenia: CS sepsis was associated with thrombocytopenia (501 [IQR, 398-621] vs 788 [IQR, 693-812] g/L; P < .001), leukopenia (2.1 [IQR, 1.7-3.0] vs 4.6 [IQR, 3.2-5.8] g/L; P < .001) (Figure 2B, C), and a systemic inflammatory response with increased IL-6 (14.4 [IQR, 5.9-20.1] vs 0 [IQR, 0-0.1] ng/mL; P < .001) (Figure 2D), TNF-α (11.7 [IQR, 3.1-25.9] vs 0 [IQR, 0-0] pg/mL; P = .037) (Figure 2E), and IL-10 (280.4 [IQR, 84.0-803.1] vs 0 [IQR, 0-0.1] pg/mL; P = .016).