Pseudoxanthoma elasticum (PXE), also known as Gronblad-Strandberg syndrome, is a rare autosomal recessive connective tissue disorder [1] mainly caused by pathogenic variants in the ABCC6 gene, leading to calcification and fragmentation of elastic fibers in multiple systems such as the skin, retina, and vasculature. This evidence concerns the gene ABCC6 and pseudoxanthoma elasticum (inherited or acquired).