SDHD and leprosy: In this regard,active case detection among household, social,and school contacts has proven to be a highly effective strategy foridentifying new cases of leprosy, with the highest incidence observedin both high- and low-endemicity areas. Moreover, longitudinal follow-up of seropositive contacts, particularlyfor PGL-1, demonstrates a high likelihood of detecting new activecases. Consequently, monitoring antibodylevels against our identified peptides offers promising potentialas accessible, efficient, and cost-effective biomarkers with the addedbenefit of predicting disease progression.