IL6 and Sepsis: Dilli and Dilmen also demonstrated that elevated interleukin-6 and C-reactive protein levels were correlated with decreased thyroid hormone concentrations in preterm infants with non-thyroidal illness, supporting the role of inflammatory cytokines in the suppression of thyroid function during sepsis [20]. However, because antibiotic-related effects on thyroid function have not been consistently demonstrated in neonatal populations, this interpretation remains speculative, and we acknowledge this uncertainty.