CD8A and head and neck squamous cell carcinoma: Consistent with previous studies, our results show that higher STATH expression in HPV-positive HNSCC tumors is correlated with increased infiltration of B cells, CD8+ T cells, and dendritic cells, reflecting a stronger antitumor immune response and likely contributing to the better overall survival observed in the HPV-positive group (HR=0.822, log-rank p=0.039), emphasizing the potential of STATH as a prognostic biomarker specifically in HPV-positive HNSCC patients [30].