The BET family is composed by BRD2, BRD3, BRD4, and BRDT, and plays important roles in cancer by directly regulating the expression of cancer-related genes such as MYC (Bandopadhayay et al., 2014), and the transcription factor NF-κB (Hajmirza et al., 2018). The gene discussed is NFKB1; the disease is cancer.