Ginger-derived PEVs have been reported to encapsulate bioactive constituents, including 6-gingerol and 10-gingerol, which exert anti-inflammatory and anti-cancer effects through the modulation of the nuclear factor-kappa B (NF-κB) and phosphatidylinositol 3’-kinase/Akt (PI3K/Akt) signaling pathways[61]. The gene discussed is AKT1; the disease is cancer.