BCHE and hypertensive disorder: PSCI is currently treated with a multifaceted approach that includes pharmacological interventions (cholinesterase inhibitors or NMDA receptor antagonists may improve cognition, although the evidence is limited; some patients may try nimodipine or ginkgo biloba), non-pharmacological therapies (such as cognitive rehabilitation and lifestyle modification), and etiological treatment (control of vascular risk factors like hypertension and diabetes, and use of antiplatelet or anticoagulant therapy to prevent recurrent strokes).