This method of training is more metabolically efficient, as it requires less energy to produce the same force.22 In addition to musculoskeletal benefits, eccentric exercises are known to enhance insulin sensitivity, promote muscle regeneration, improve lipid profiles, increase cortical excitability, and boost cardiorespiratory fitness.17 Owing to these systemic effects, eccentric exercises have been utilized in managing conditions such as type 2 diabetes, sarcopenia, and cardiorespiratory disorders.17 This evidence concerns the gene INS and sarcopenia.