EV-A71 infection induced IL-12 in both WT and IL-20RA-/- mice, with reduced serum IL-12 levels detected in WT mice when compared to IL-20RA-/- mice from 1 to 5 d.p.i., with significant differences found on 3 and 5 d.p.i. (Figure 5A). This evidence concerns the gene IL20RA and infection.