SHMT2 and Anxiety: Similarly, for anxiety specifically, mediating effects were observed through WBC, platelets, neutrophils, CRP, and GlyA, with composite indices NLR, SII, SIRI, and INFLA, with intermediate ratios of 2.85, 1.40, 3.57, 3.66, 3.59, and 1.70%, 2.48, 2.05, 5.92%, respectively.