In neonatal sepsis, Engade et al. (n = 120) reported significantly lower PCR values in septic vs. non-septic infants on day 3 (1.49 vs. 4.5 × 109/mg) and day 5 (0.97 vs. 4.3 × 109/mg) (P = 0.04) (24); Jin et al. (n = 1,385) further identified that the PCR serves as an independent predictor of sepsis, exhibiting better predictive performance (AUC 0.73) compared to CRP (AUC 0.68) or platelet count alone (AUC 0.67) (12). The gene discussed is CRP; the disease is Neonatal sepsis.