Given that age (OR 1.04, 95% CI 1.00–1.10, p = 0.05), sex (OR 1.26, 95% CI 1.20–1.33, p < 0.001), BMI (OR 1.07, 95% CI 1.06–1.07, p < 0.001), T2D (OR 4.17, 95% CI 3.89–4.46, p < 0.001), alcohol intake (OR 2.92, 95% CI 1.00–9.82, p < 0.001) and PNPLA3 rs738409 genotypes (OR 1.37, 95% CI 1.32–1.43, p < 0.001) associated with the risk of prevalent CLD, we stratified the analysis according to these risk factors. This evidence concerns the gene PNPLA3 and congenital secretory chloride diarrhea 1.