Lastly, Zhou et al. (2020) showed that miR‐103a‐3p is highly expressed in PD patient brain and plasma samples, as well as in MPTP‐induced mice and MPP+‐treated SH‐SY5Y cells, where it binds the 3′‐UTR of PRKN to downregulate Parkin and Ambra1, impairing mitophagy and leading to accumulation of dysfunctional mitochondria. This evidence concerns the gene PRKN and Parkinson disease.