AMBRA1 and Parkinson disease: Lastly, Zhou et al. (2020) showed that miR‐103a‐3p is highly expressed in PD patient brain and plasma samples, as well as in MPTP‐induced mice and MPP+‐treated SH‐SY5Y cells, where it binds the 3′‐UTR of PRKN to downregulate Parkin and Ambra1, impairing mitophagy and leading to accumulation of dysfunctional mitochondria.